Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0308181
PubChem CID
Molecular Formula
C5H3NO5
Molecular Weight
157.081 g/mol
Synonyms/Alias
[5-NITRO-2-FUROIC ACID; 645-12-5; 5-Nitrofuran-2-carboxylic acid; Nitrofurate; 5-Nitrofuroic acid; 5-Nitro-2-furancarboxylic Acid; 2-Furoic acid; 5-nitro-; 2-Furancarboxylic acid; 5-nitro-; 5-Nitrofur...
InChI Key
IODMEDPPCXSFLD-UHFFFAOYSA-N
InChI
InChI=1S/C5H3NO5/c7-5(8)3-1-2-4(11-3)6(9)10/h1-2H,(H,7,8)
IUPAC Name
5-nitrofuran-2-carboxylic acid
CAS Number
1874-23-3

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

14 14 0 0 0 0 0 0 0 0999 V2000
0.2509 -1.2616 0.5627 C 0 0 0 0 0 0 0 0 0 0 0 0
0.7903 -0.1069 0.0222 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.1681 0.722...

Experimental Data

Activity Data

Target Ion Channel
Aquaporin-1
Uniprot Accession Number
Function
Blocker
Species
Homo sapiens (Human)
IC50
IC50: 1200 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
Not mention
Holding Potential
−110 to 60 mV mV
Temperature
Not mention
Test Method
Patch-clamping
Test Species
Xenopus laevis oocyte

Binding Information

Binding Site
Transmembrane domain
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
11
Rotatable Bonds
2
logP
0.886
Complexity
32.3217
TPSA (Ų)
93.58
H-Bond Donors
1
H-Bond Acceptors
4
Ring Count
1
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